组蛋白去甲基化酶赖氨酸MINA抗体
产品名称： 组蛋白去甲基化酶赖氨酸MINA抗体
英文名称： MINA53
产品编号： hz-18941R
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
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Rabbit Anti-MINA53 antibody
| 产品编号 | hz-18941R |
| 英文名称 | MINA53 |
| 中文名称 | 组蛋白去甲基化酶赖氨酸MINA抗体 |
| 别 名 | 60S ribosomal protein L27a histidine hydroxylase; Bifunctional lysine specific demethylase and histidyl hydroxylase MINA; FLJ14393; Histone lysine demethylase MINA; MDIG; MINA; MINA_HUMAN; Mineral dust-induced gene protein; Myc induced nuclear antigen 53 kDa; MYC induced nuclear antigen; MYC-induced nuclear antigen; NO52; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX. |
| 产品类型 | 甲基化抗体 |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MINA53:251-350/465 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008] Function: Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. Subcellular Location: Nucleus. Nucleus; nucleolus. Tissue Specificity: Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines. Similarity: Belongs to the MINA53/NO66 family. Contains 1 JmjC domain. Gene ID: 84864 Database links: Entrez Gene: 84864 Human Entrez Gene: 67014 Mouse Omim: 612049 Human SwissProt: Q8IUF8 Human SwissProt: Q8CD15 Mouse Unigene: 570562 Human Unigene: 607776 Human Unigene: 289150 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |