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上海信裕生物科技有限公司
DOK3抗体

DOK3抗体

商家询价

产品名称： DOK3抗体

英文名称： DOK3Antibody

产品编号： XY15749-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 DOK3抗体

Applications
Tested Applications: ELISA, WB, IHC
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in Jurkat cells
Positive IHC detected in Human lymphoma tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
DOK3抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 15749-1-AP;Jurkat cellJurkat cells were subjected to SDS PAGE followed by western blot with 15749-1-AP(DOK3 antibody) at dilution of 1:800
  • 15749-1-AP;LymphomaImmunohistochemical of paraffin-embedded human lymphoma using 15749-1-AP(DOK3 antibody) at dilution of 1:50 (under 10x lens)
  • 15749-1-AP;LymphomaImmunohistochemical of paraffin-embedded human lymphoma using 15749-1-AP(DOK3 antibody) at dilution of 1:50 (under 40x lens)
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen InformationDOK3抗体
Immunogen: DOK3 fusion protein ag8221 Full Name: Docking protein 3
Caculated Molecular
Weight:		 496aa,53 kDa;330aa,36 kDa Observed Molecular 
Weight:		 53kd
GenbankNo BC004564 GeneID: 79930
Symbol DOK3 Synonyms Docking protein 3, DOK3, DOKL, FLJ22570, FLJ39939
Background

The adaptor proteins downstream of kinase 1 (DOK1) to DOK3 are mainly found in immune cells, and they are closely related, with some functional redundancy, although each DOK protein has distinct properties and functions. DOK1 to DOK3 inhibit LPS responses. DOK proteins have an N-terminal pleckstrin homology (PH) domain, a phosphotyrosine-binding (PTB) domain, and four tyrosine-containing motifs that can bind to Src homology 2 (SH2) domains when phosphorylated. DOK3 was also shown to have an inhibitory role as it restricts Ca2+ and JNK activation in B cell receptor signaling. The MW of this protein is 53 kDa, and this antibody specially recognises the 53 kDa protein.DOK3抗体

Rattus norvegicus (Rat)

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XY059Hu21 帕金森氏病蛋白7(PARK7)单克隆抗体 Monoclonal Antibody to Parkinson Disease Protein 7 (PARK7) Homo sapiens (Hukl)

XY060Hu21 帕金森氏病蛋白2(PARK2)单克隆抗体 Monoclonal Antibody to Parkinson Disease Protein 2 (PARK2) Homo sapiens (Hukl)

XY074Hu21 泛素蛋白连接酶E3成分N-识别蛋白4(UBR4)单克隆抗体 Monoclonal Antibody to Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) Homo sapiens (Hukl)

XY087Hu21 含WW域E3泛素蛋白连接酶2(WWP2)单克隆抗体 Monoclonal Antibody to WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) Homo sapiens (Hukl)

XY096Hu21 细胞程序性死亡蛋白6(PDCD6)单克隆抗体 Monoclonal Antibody to Programmed Cell Death Protein 6 (PDCD6) Homo sapiens (Hukl)

XY105Hu21 细胞程序性死亡蛋白5(PDCD5)单克隆抗体 Monoclonal Antibody to Programmed Cell Death Protein 5 (PDCD5) Homo sapiens (Hukl)

XY113Hu21 成纤维细胞生长因子受体样蛋白1(FGFRL1)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor Receptor Like Protein 1 (FGFRL1) Homo sapiens (Hukl)

XY118Hu21 Wolfram综合征蛋白1(WFS1)单克隆抗体 Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) Homo sapiens (Hukl)

XY118Ra21 Wolfram综合征蛋白1(WFS1)单克隆抗体 Monoclonal Antibody to Wolfram Syndrome Protein 1 (WFS1) Rattus norvegicus (Rat)

XY122Hu21 GM2神经节苷脂激活因子(GM2A)单克隆抗体 Monoclonal Antibody to GM2 Ganglioside Activator (GM2A) Homo sapiens (Hukl)

XY139Hu21 尼曼病蛋白C2(NPC2)单克隆抗体 Monoclonal Antibody to Niekln Pick Disease Type C2 (NPC2) Homo sapiens (Hukl)

XY148Hu21 Notch同源物2(NOTCH2)单克隆抗体 Monoclonal Antibody to Notch Homolog 2 (NOTCH2) Homo sapiens (Hukl)

XY178Hu21 G补缀FHA域血管生成因子1(AGGF1)单克隆抗体 Monoclonal Antibody to Angiogenic Factor With G Patch And FHA Domains 1 (AGGF1) Homo sapiens (Hukl)

XY178Ra21 G补缀FHA域血管生成因子1(AGGF1)单克隆抗体 Monoclonal Antibody to Angiogenic Factor With G Patch And FHA Domains 1 (AGGF1) Rattus norvegicus (Rat)

XY222Hu21 自噬相关蛋白7(ATG7)单克隆抗体 Monoclonal Antibody to Autophagy Related Protein 7 (ATG7) Homo sapiens (Hukl)

XY230Ra21 AXL受体酪氨酸激酶(AXL)单克隆抗体 Monoclonal Antibody to AXL Receptor Tyrosine Kinase (AXL) Rattus norvegicus (Rat)