TNFSF18 Pre-design Chimera RNAi
产品名称： TNFSF18 Pre-design Chimera RNAi
英文名称： TNFSF18 Pre-design Chimera RNAi
产品编号： H00008995-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Homo sapiens tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_005092
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 8995
- Gene Name:
- TNFSF18
- Gene Alias:
- AITRL,GITRL,MGC138237,TL6,hGITRL
- Gene Description:
- tumor necrosis factor (ligand) superfamily, member 18
- Omim ID:
- 603898
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq
- Other Designations:
- AITR ligand,GITR ligand,glucocorticoid-induced TNFR-related protein ligand
- Gene Pathway
- Related Disease
- Birth Weight
- Cardiovascular Diseases
- Crohn Disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Hematologic Diseases
- Hepatitis C
- Hodgkin Disease
- Inflammatory Bowel Diseases
- Leukemia
- Leukemia, Myeloid, Acute
- Lymphoproliferative Disorders
- Meningeal Neoplasms
- Meningioma
- Multiple Myeloma
- Occupational Diseases