FITC标记的α微管蛋白乙酰转移酶1抗体
产品名称： FITC标记的α微管蛋白乙酰转移酶1抗体
英文名称： Anti-α-TAT/FITC
产品编号： HZ-9535R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-α-TAT/FITC Conjugated antibody
FITC标记的α微管蛋白乙酰转移酶1抗体
| 产品编号 | bs-9535R-FITC |
| 英文名称 | Anti-α-TAT/FITC |
| 中文名称 | FITC标记的α微管蛋白乙酰转移酶1抗体 |
| 别 名 | C6orf134; Acetyltransferase mec 17 homolog; Alpha TAT; Alpha tubulin acetyltransferase 1; Alpha tubulin N acetyltransferase; Chromosome 6 open reading frame 134; Hypothetical protein LOC79969; MEC17; Nbla00487; TAT; ATAT_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human alpha-TAT |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf134 gene product has been provisionally designated C6orf134 pending further characterization. Function: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development. Similarity: Belongs to the acetyltransferase ATAT1 family. Database links: Entrez Gene: 79969 Human Entrez Gene: 73242 Mouse Entrez Gene: 361789 Rat SwissProt: Q9H8X5 Human SwissProt: Q8K341 Mouse SwissProt: Q6MG11 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在人类基因组的近6%中，6号染色体包含1亿7000万个碱基对序列中大约1200个基因。缺失6号染色体Q臂的一部分与早期发病的肠癌相关，提示存在癌症易感性位点。迟发性卟啉症与迟发性卟啉症是通过HFE基因与6号染色体相关的，HFE基因在突变时易使个体发展成这种卟啉症。值得注意的是，与帕金森病相关的PARK2基因和编码主要组织相容性复合体蛋白的基因，它们是免疫系统的关键分子成分，并确定风湿性疾病的易感性，也位于6号染色体上。Stutkle综合征、21羟化酶缺乏症和枫糖浆尿病也与6号染色体上的基因有关。在6号染色体Q臂上发现了双相情感障碍易感基因位点。C6OF134基因产物已暂时指定为C6ORF 134，有待进一步鉴定。