FITC标记的蛋白酶激活受体4抗体
产品名称： FITC标记的蛋白酶激活受体4抗体
英文名称： Anti-Proteinase-activated receptor 4/PAR4/FITC
产品编号： HZ--9511R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Proteinase-activated receptor 4/PAR4/FITC Conjugated antibody
FITC标记的蛋白酶激活受体4抗体
| 产品编号 | bs-9511R-FITC |
| 英文名称 | Anti-Proteinase-activated receptor 4/PAR4/FITC |
| 中文名称 | FITC标记的蛋白酶激活受体4抗体 |
| 别 名 | F2RL3; F2R Like Thrombin/Trypsin Receptor 3; Coagulation Factor II (Thrombin) Receptor-Like 3; Thrombin Receptor-Like 3; PAR-4; PAR4; Coagulation Factor II Receptor-Like 3; Proteinase-Activated Receptor-4; Proteinase-Activated Receptor 4; Protease-Activated Receptor-4; PAR4_HUMAN; |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Proteinase-activated receptor 4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008] Function: Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets. Post-translational modifications: A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 9002 Human Omim: 602779 Human SwissProt: Q96RI0 Human Unigene: 137574 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
凝血因子II（凝血酶）受体样3（F2RL3）是与鸟嘌呤核苷酸结合蛋白偶联的7跨膜区受体家族的一员。F2RL3也是蛋白酶激活受体家族的成员。F2RL3通过其胞外氨基末端的蛋白水解裂解而激活。新的氨基末端起着拴系配体的作用，并激活受体。F2RL3由凝血酶和胰蛋白酶激活。[ RefSeq，JUL 2008 ]