FITC标记的线粒体内膜蛋白抗体
产品名称： FITC标记的线粒体内膜蛋白抗体
英文名称： Anti-Mitofilin/FITC
产品编号： HZ-1824R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Mitofilin/FITC Conjugated antibody
FITC标记的线粒体内膜蛋白抗体
| 英文名称 | Anti-Mitofilin/FITC |
| 中文名称 | FITC标记的线粒体内膜蛋白抗体 |
| 别 名 | Cell proliferation inducing protein 52; Cell proliferation-inducing gene 4/52 protein; HMP; IMMT; IMMT_HUMAN; Inner membrane protein mitochondrial; Inner mitochrondial membrane; MINOS2; Mitochondrial inner membrane organizing system 2; Mitochondrial inner membrane protein; Mitofilin; Motor protein; p87; p87/89; p89; pig4; PIG52; Proliferation-inducing gene 4; MICOS complex subunit MIC60. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 信号转导 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 68kDa |
| 细胞定位 | 细胞膜 线粒体 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Mitofilin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology. Mitofilin was originally described as heart muscle protein (HMP) because of its high expression in the heart. Subunit: Interacts with OPA1, preferentially with the soluble OPA1 form. Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2. Interacts with CHCHD6; the interaction is direct. Subcellular Location: Mitochondrion inner membrane. Database links: Entrez Gene: 508853 Cow Entrez Gene: 10989 Human Entrez Gene: 76614 Mouse Entrez Gene: 312444 Rat Omim: 600378 Human SwissProt: Q16891 Human SwissProt: Q8CAQ8 Mouse SwissProt: Q3KR86 Rat Unigene: 148559 Human Unigene: 235123 Mouse Unigene: 47124 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
线粒体是细胞能量生产和主要代谢反应的中心。不同物种、不同组织和不同代谢状态的线粒体作为双膜结合的细胞器，在自然界中具有高度多态性，但表现出共同的结构特征。线粒体结构的超微结构变化主要是由于嵴的数量和形状不同造成的。在能量需求较高的组织线粒体中发现大量嵴。对人心脏线粒体蛋白质组的分析表明，线粒体蛋白是最丰富的线粒体蛋白之一。它在维持嵴形态方面起着重要作用。丝裂霉素因其在心脏中的高表达而最初被描述为心肌蛋白（HMP）。