Breakthrough Diagnostic Test Detects 18 Respiratory-技术前沿-资讯-生物在线

Breakthrough Diagnostic Test Detects 18 Respiratory

作者：纽罗西敏生物科技 2007-09-22T00:00 (访问量:7066)

Breakthrough Diagnostic Test Detects 18 Respiratory Infections
With another potentially virulent flu season approaching, Seegene Inc, Rockville, Md, has introduced a multiplex-formatted diagnostic test covering the most common virus and bacteria respiratory infections in a single reaction tube. The Seeplex 18-plex Respiratory Test is the only diagnostic test capable of simultaneously detecting 18 of the most prevalent respiratory virus- and bacteria-born infections in a single test. The test detects 11 respiratory RNA viruses, two DNA viruses, and five pneumonia bacteria from samples including nasopharyngeal aspirates, nasopharyngeal swabs and bronchoalveolar lavage.

By enabling healthcare personnel to test for 18 different pathogens for a cost similar to testing for a single pathogen, the Seeplex test breaks the mold of a ‘single pathogen, single test’ regimen and high false-positives/negatives results associated with conventional multiplexing. Traditional tests, such as viral culture and Ag-Ab tests, are laborious and time consuming. The new test eliminates these drawbacks by multiplexing without cross reactivity and achieving rapid test results.

The test detects influenza A virus; influenza B virus; respiratory syncytial virus A; respiratory syncytial virus B; parainfluenzae virus 1; parainfluenzae virus 2; parainfluenzae virus 3; coronavirus 229E/NL63; coronavirus OC43/HKU1; human rhinovirus; enterovirus; adenovirus; bocavirus; legionella pneumoniae; streptococcus pneumoniae; chlamydophila pneumoniae; haemophilus influenzae; and mycoplasma pneumoniae.

The Seeplex Test aspires to become an essential tool for active surveillance and treatment of respiratory illnesses. The use of this new diagnostic test enables healthcare personnel to rapidly determine whether a patient’s respiratory ailment is caused by virus or bacteria, and subsequently prescribe the best course of treatment whether an antibiotic, antiviral or bed rest.

"Our new 18-plex Respiratory Test is what the clinical health care industry has been asking for – the ability to routinely test for a wide spectrum of respiratory pathogens in a single test, at the price of a single pathogen test," stated Jong-Yoon Chun, founder and CEO, Seegene. "Like our other commercially available tests, notably the recently introduced 18-plex test for human papillomaviruses, our new respiratory test is simply performed with one multiplex PCR in a single tube and capillary electrophoresis for automated detection of pathogens. These tests use Seegene’s proprietary DPO (Dual Priming Oligo) primer system, ensuring test reproducibility, specificity and sensitivity."

Seeplex is a multiplexing PCR technology that enables simultaneous multipathogen detection. It works in combination with automatic detection systems such as Capillary Electrophoresis.

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